CuraScript, Inc., Express Scripts Specialty Pharmacy, dispenses specialty medications to people with major
medical conditions and provides other personalized services. Through CuraScript, patients receive highly
technical care delivered in a personal manner to help them manage their health and get the most from
Arestin Added to Specialty Drug List OraPharma's Arestin® (minocycline hydrochloride) Microspheres, 1mg is a tetracycline antibiotic approved for certain oral procedures in adult patients with periodontitis. It is supplied as a dry powder in unit-dose cartridges and is administered by a healthcare professional. Arestin is exclusively available through CVS/Caremark. More information can be found at:
Cuvposa Added to Specialty Drug List Shionogi Pharma's Cuvposa™ (glycopyrrolate oral solution) 1mg/5mL was approved by the U.S. Food and Drug Administration (FDA) in July 2010. It is an anticholinergic medication indicated to reduce chronic drooling in patients 3-16 years of age with neurologic conditions associated with problem drooling (e.g., cerebral palsy). It is only available through Diplomat Specialty Pharmacy. Because this was identified as a limited distribution medication, it was added to the specialty drug list. Erwinaze Added to Specialty Drug List On Nov. 18, 2011, Eusa Pharma received approval from the U.S. Food and Drug Administration (FDA) for its orphan drug Erwinaze™ (asparaginase Erwinia chrysanthemi) for the treatment of acute lymphoblastic leukemia (ALL) in patients with hypersensitivity to E.coli-derived asparaginase. ALL is the most common childhood cancer with approximately 2,900 patients younger than 20 years of age diagnosed each year in the United States. Between 15% and 20% of patients develop hypersensitivity to E.coli-derived asparaginase, preventing continued treatment. Erwinaze is administered as an intramuscular injection. Eusa launched Erwinaze upon approval. Eylea Added to Specialty Drug List On November 18, 2011, Regeneron received approval from the U.S. Food and Drug Administration (FDA) for Eylea™ (aflibercept) Injection for the treatment of patients with neovascular (wet) age-related macular degeneration (AMD). Eylea is a biologic drug known as a vascular endothelial growth factor [(VEGF) or angiogenesis] inhibitor that works by blocking the formation of new blood vessels in the back of the eye. Eylea is administered as injection into the back of the eye by a healthcare professional. The recommended dose for Eylea is 2mg once monthly for three months followed by 2mg every other month. Regeneron launched Eylea shortly after approval. Eylea costs $1850 per injection. It is available through a limited number of specialty pharmacies and distributors, including CuraScript Specialty Pharmacy and Specialty Distribution. Ferriprox Added to Specialty Drug List On October 14, 2011, ApoPharma received accelerated approval from the U.S. Food and Drug Administration (FDA) for Ferriprox® (deferiprone) to treat patients with iron overload due to blood transfusion in patients with thalassemia who have had an inadequate response to prior chelation therapy. Thalassemia is a genetic blood disorder in which the body makes an abnormal form of hemoglobin (protein in red blood cells that carries oxygen), which results in
anemia. Patients with thalassemia require frequent blood transfusions to treat their anemia; however the blood transfusions can cause an excess build-up of iron in the body. Ferriprox is an oral chelator, which binds to and removes heavy metals (e.g., iron) from the body. The recommended dose of Ferriprox is 25mg/kg to 33mg/kg orally three times daily. It is supplied as 500mg film-coated scored tablets. Ferriprox is exclusively available through Centric.
Nexplanon Added to Specialty Drug List On Nov. 9, Merck announced the release of Nexplanon® in the United States. It is expected that this new product will eventually replace Implanon™, a similar Merck product. Like Implanon, Nexplanon is a long-acting, progestin-only, single-rod etonogestrel (68mg) reversible hormonal implant contraceptive. Once properly placed, the implant is effective at preventing pregnancy for up to three years, at which time it must be removed or replaced. Upon removal, pregnancy can occur within as little as 7-14 days. Nexplanon differs from Implanon in that it is a radiopaque implant that can be detected by palpation, two-dimensional X-ray, computed tomography (CT scan), ultrasound scanning (USS), or magnetic resonance imaging (MRI). Implanon can only be detected by palpation, USS or MRI. Nexplanon is available through a limited number of specialty pharmacies including CuraScript. Pricing Claims will be processed according to your existing drug coverage rules. If you have questions regarding the drug-list changes, pricing for the added drug or would like to alter your drug coverage rules, please contact your Express Scripts Account Management team. Definition of a Specialty Drug: Specialty drugs are injectable and non-injectable drugs defined as having one or more of several key characteristics, including:
Requirement for frequent dosing adjustments and intensive clinical monitoring to
decrease the potential for drug toxicity and increase the probability for beneficial treatment outcomes.
Need for intensive patient training and compliance assistance to facilitate therapeutic
Limited or exclusive product availability and distribution.
Specialized product handling and/or administration requirements.
Cost in excess of $500 for a 30-day supply.
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Department of Strategy and PolicyNational University of Singapore15 Kent Ridge DriveSINGAPORE, 119245Ph.D. (Economics), Indiana University, April, 2005M.A. (Economics), Indiana University, February, 2003M.Sc (Management), National University of Singapore, September, 2000B.E. (Management), Peking University, 1998Associate Professor (with tenure), Department of Strategy and Policy, National Uni