Publications supported by the Cell Imaging Facility-Nikon Imaging Center (accumulated and filtered to the best of our ability) Angeloni, N.L., C.W. Bond, Y. Tang, D.A. Harrington, S. Zhang, S.I. Stupp, K.E. McKenna, and C.A. Podlasek. 2011. Regeneration of the cavernous nerve by Sonic hedgehog using aligned peptide amphiphile nanofibers. Biomaterials. 32:1091-1101. Antinone, S.E., S.V. Zaichick, and G.A. Smith. 2010. Resolving the assembly state of herpes simplex virus during axon transport by live-cell imaging. J Virol. 84:13019-13030. Atherton, J.F., K. Kitano, J. Baufreton, K. Fan, D. Wokosin, T. Tkatch, R. Shigemoto, D.J. Surmeier, and M.D. Bevan. 2010. Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus. J Neurosci. 30:16025-16040. Aurora, A.B., D. Biyashev, Y. Mirochnik, T.A. Zaichuk, C. Sanchez-Martinez, M.A. Renault, D. Losordo, and O.V. Volpert. 2010. NF-kappaB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement. Blood. 116:475-484. Aviles, M.O., C.H. Lin, M. Zelivyanskaya, J.G. Graham, R.M. Boehler, P.B. Messersmith, and L.D. Shea. 2010. The contribution of plasmid design and release to in vivo gene expression fol owing delivery from cationic polymer modified scaffolds. Biomaterials. 31:1140-1147. Barlan, K., and V.I. Gelfand. 2010. Intracel ular transport: ER and mitochondria meet and greet along designated tracks. Curr Biol. 20:R845-847. Batl e, D., M. Jose Soler, and M. Ye. 2010. ACE2 and diabetes: ACE of ACEs? Diabetes. 59:2994-2996. Bayeva, M., and H. Ardehali. 2010. Mitochondrial dysfunction and oxidative damage to sarcomeric proteins. Curr Hypertens Rep. 12:426-432. Bensenor, L.B., K. Barlan, S.E. Rice, R.G. Fehon, and V.I. Gelfand. 2010. Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants. Proc Natl Acad Sci U S A. 107:7311-7316. Bhattacharyya, S., K.L. Warfield, G. Ruthel, S. Bavari, M.J. Aman, and T.J. Hope. 2010. Ebola virus uses clathrin-mediated endocytosis as an entry pathway. Virology. 401:18-28. Bieging, K.T., M. Swanson-Mungerson, A.C. Amick, and R. Longnecker. 2010. Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2A. Cell Cycle. 9:901-908. Biyashev, D., D. Veliceasa, A. Kwiatek, M.M. Sutanto, R.N. Cohen, and O.V. Volpert. 2010. Natural angiogenesis inhibitor signals through Erk5 activation of peroxisome proliferator-activated receptor gamma (PPARgamma). J Biol Chem. 285:13517-13524. Bizhanova, A., and P. Kopp. 2010. Genetics and phenomics of Pendred syndrome. Mol Cell Endocrinol. 322:83-90. Blatner, N.R., A. Bonertz, P. Beckhove, E.C. Cheon, S.B. Krantz, M. Strouch, J. Weitz, M. Koch, A.L. Halverson, D.J. Bentrem, and K. Khazaie. 2010. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci U S A. 107:6430-6435. Bosman, J.D., F. Yehiely, J.R. Evans, and V.L. Cryns. 2010. Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer. Breast Cancer Res Treat. 119:63-70. Brown, J.B., G. Lee, E. Managlia, G.R. Grimm, R. Dirisina, T. Goretsky, P. Cheresh, N.R. Blatner, K. Khazaie, G.Y. Yang, L. Li, and T.A. Barrett. 2010. Mesalamine inhibits epithelial beta-catenin activation in chronic ulcerative colitis. Gastroenterology. 138:595-605, 605 e591-593. Brubaker, C.E., H. Kissler, L.J. Wang, D.B. Kaufman, and P.B. Messersmith. 2010. Biological performance of mussel-inspired adhesive in extrahepatic islet transplantation. Biomaterials. 31:420-427. Bryan, N.B., A. Dorfleutner, S.J. Kramer, C. Yun, Y. Rojanasakul, and C. Stehlik. 2010. Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. J Inflamm (Lond). 7:23. Budinger, G.R., G.M. Mutlu, D. Urich, S. Soberanes, L.J. Buccel ato, K. Hawkins, S.E. Chiarel a, K.A. Radigan, J. Eisenbart, H. Agrawal, S. Berkelhamer, S. Hekimi, J. Zhang, H. Perlman, P.T. Schumacker, M. Jain, and N.S. Chandel. 2010. Epithelial Cel Death is an Important Contributor to Oxidant-Mediated Acute Lung Injury. Am J Respir Crit Care Med. Bulun, S.E., Y.H. Cheng, M.E. Pavone, Q. Xue, E. Attar, E. Trukhacheva, H. Tokunaga, H. Utsunomiya, P. Yin, X. Luo, Z. Lin, G. Imir, S. Thung, E.J. Su, and J.J. Kim. 2010. Estrogen receptor-beta, estrogen receptor-alpha, and progesterone resistance in endometriosis. Semin Reprod Med. 28:36-43. Burt, R.K., A. Testori, Y. Oyama, H.E. Rodriguez, K. Yaung, M. Vil a, J.M. Bucha, F. Milanetti, J. Sheehan, N. Rajamannan, and W.H. Pearce. 2010. Autologous peripheral blood CD133+ cel implantation for limb salvage in patients with critical limb ischemia. Bone Marrow Transplant. 45:111-116. Calve, S., S.J. Odelberg, and H.G. Simon. 2010. A transitional extracel ular matrix instructs cell behavior during muscle regeneration. Dev Biol. 344:259-271. Camarata, T., D. Snyder, T. Schwend, J. Klosowiak, B. Holtrup, and H.G. Simon. 2010. Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development. BMC Dev Biol. 10:104. Camarata, T., J. Krcmery, D. Snyder, S. Park, J. Topczewski, and H.G. Simon. 2010. Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation. Dev Biol. 337:233-245. Carrol , R.W., M.S. Wainwright, K.Y. Kim, T. Kidambi, N.D. Gomez, T. Taylor, and K. Haldar. 2010. A rapid murine coma and behavior scale for quantitative assessment of murine cerebral malaria. PLoS One. 5. Chi, A.Y., G.B. Waypa, P.T. Mungai, and P.T. Schumacker. 2010. Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells. Antioxid Redox Signal. 12:603-610. Christie, L.A., T.A. Russel , J. Xu, L. Wood, G.M. Shepherd, and A. Contractor. 2010. AMPA receptor desensitization mutation results in severe developmental phenotypes and early postnatal lethality. Proc Natl Acad Sci U S A. 107:9412-9417. Comel as, A.P., A.M. Kel y, H.E. Trejo, A. Briva, J. Lee, J.I. Sznajder, and L.A. Dada. 2010. Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process mediated by the action of Akt. J Cel Sci. 123:1343-1351. Cooley, A., S. Zelivianski, and J.S. Jeruss. 2010. Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines. Cell Cycle. 9:4900-4907. Dasgupta, B., T. Chew, A. deRoche, and W.A. Mul er. 2010. Blocking platelet/endothelial cel adhesion molecule 1 (PECAM) inhibits disease progression and prevents joint erosion in established collagen antibody-induced arthritis. Exp Mol Pathol. 88:210-215. De Laporte, L., A. Huang, M.M. Ducommun, M.L. Zelivyanska, M.O. Aviles, A.F. Adler, and L.D. Shea. 2010. Patterned transgene expression in multiple-channel bridges after spinal cord injury. Acta Biomater. 6:2889-2897. Decker, R.S., A.K. Rines, S. Nakamura, T.J. Naik, J.A. Wassertsrom, and H. Ardehali. 2010. Phosphorylation of contractile proteins in response to alpha- and beta-adrenergic stimulation in neonatal cardiomyocytes. Transl Res. 155:27-34. Deng, J., N. Jin, X. Yin, G.Y. Yang, Z. Zhang, R.A. Omary, and A.C. Larson. 2010. Quantitative multiparametric PROPELLER MRI of diethylnitrosamine-induced hepatocarcinogenesis in wister rat model. J Magn Reson Imaging. 31:1242-1251. Desireddi, J.R., K.N. Farrow, J.D. Marks, G.B. Waypa, and P.T. Schumacker. 2010. Hypoxia increases ROS signaling and cytosolic Ca(2+) in pulmonary artery smooth muscle cells of mouse lungs slices. Antioxid Redox Signal. 12:595-602. Egerer, M., and K.J. Satchell. 2010. Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins. 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Zavecsa-h-435-psu -045 pi-en-clean

SUMMARY OF PRODUCT CHARACTERISTICS NAME OF THE MEDICINAL PRODUCT Zavesca 100 mg hard capsules 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each capsule contains 100 mg miglustat. For the full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM Hard capsule. White capsules with “OGT 918” printed in black on the cap and “100” printed in black on the b

The slaughter and killing of animals

Position on Castration of Piglets Introduction About 100 million male pigs are castrated in the EU every year, most of the time through surgical methods without anaesthesia and analgesia, raising major welfare concerns. Castration without anaesthesia is always a painful and stressful procedure even if pain killers are used before or after the surgical act, and is not acceptable from

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