M.sc.-organic chemistry

Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-III (Chemistry)
Organic Chemistry
In force from June-2008
Total Marks: 100

Paper-IX
Natural Product-I
Lectures: 60

Unit – I
Carbohydrates:
12
Introduction, classification, types of glycosidic linkage, configuration of mono saccharides, ring structure of mono saccharides, disaccharides: lactose and maltose, polysaccharides: starch and cellulose, glycosides: salicin, indican and amygldalin, photosynthesis.
Unit – II
Vitamins:
12
General introduction and classification, role of vitamins in biochemical reactions, vitamin A group, vitamin C and vitamin E group (α, β, γ and δ tocopherols), vitamin K group.
Unit – III
Alkaloids:
12
Introduction, classification and general methods used for determination of structure of alkaloids, structure and synthesis of atropine, quinine and narcotine. Structure of strychnine and reserpine (analytical evidences only)
Unit – IV
Amino acids and polypeptides:
12
Introduction and classification of amino acids, a modern approach for the synthesis of polypeptides, general synthesis and different methods of synthesis, amino acids sequence determination in polypeptide, modern synthetic approach for end group analysis, illustration of polypeptide synthesis with amino acids arranged in a particular sequence.
Unit – V
Isoprenoids:
12
Introduction and classification of Isoprenoids, isoprene rule and its importance in isoprenoid chemistry and their structure determination, sesquiterpenoids: farnesol and cadinene, constitution of phytol, constitution of abietic acid. Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-III (Chemistry)
Organic Chemistry
In force from June-2008
Total Marks: 100
Paper – X
Industrial Chemistry
Lectures: 60

Unit – I
Polymers and polymerization:
12
Definition of monomer, polymer, oligomer, HDP, LDP, filler, plastisizers and antioxidants with respect to polymer chemistry, polymeric reactions and their illustrations, addition polymerization and condensation polymerization, definition of true, natural and semi-synthetic fibers, manufacture of Viscose rayon, manufacture of phenol formaldehyde resin, manufacture of Nylon polymers and manufacture of synthetic elastomers. Unit – II
Petroleum and petrochemicals:
12
Theory of origin of petroleum and techniques for the search of petroleum, definition of petrochemicals and their importance in the day to day life, manufacture of important chemicals from C2 – cut of petroleum (at least four chemicals), manufacture of important chemicals form C3 – cut of petroleum, manufacture of important chemicals from aromatic cut of petroleum. Unit – III
Unit processes and unit operations:
12
Introduction to unit processes and unit operations, unit process of sulphontion, Unit –IV
A-Pesticides:
12
Pesticides: introduction, classification and synthesis of several pesticides,
B- Synthetic perfumes:
Brief introduction to perfumes and synthetic perfume
Unit –V
(A) Sugar, starch and paper industries:
06
Manufacture of sugar with utilization of by-products, starch and starch products, manufacture of pulp and paper. (B) Some fundamental aspects of IPR
06
Understanding of intellectual property rights, Overview of the IPR and its tools, World Trade Organization, Patent Cooperation Treaty Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-III (Chemistry)
Organic Chemistry
In force from June-2008
Total Marks: 100
Paper – XI
Selected Topics-I
Lectures: 60

Unit-I
Green Chemistry:
12
Brief introduction, principles, green catalysts-acid catalyst, basic catalyst, oxidation catalysts, polymer supported catalysts, photocatalyst, green synthesis-phase transfer catalyst, green synthesis of polycarbonates, paracetamol, ibuprofen, citral, urethane, adipic acid and styrene Unit-II
Antibiotics:
12
Introduction to antibiotics and manufacture of penicillin, streptomycin and erythromycin, chemistry of penicillins, chloromycetin and streptomycin, cephalosporins, an introduction to tertacyclines, macrolides and polypeptide antibiotics. Unit-III
(A) Explosives
04
Introduction, classification and methods to determine explosive power, synthesis and importance of different types of explosives (B) Synthetic detergents:
04
Synthetic detergents: classification, mechanism of action, large scale manufacture of detergents (C) Synthetic sweeteners
04
Synthesis synthetic of sweeteners and their importance Unit-IV
Pollution and pollution control:
12
Introduction and fundamental aspects of various pollutants from air, water and soil, purification and treatment of municipal waste water, industrial effluent in ETP, waste treatment of soil, air pollution and its control. Unit-V
Synthesis of some industrially important food colors and dyes:
12
Dyes:- Classification of Dyes. Synthesis and application of industrially important dyes, Non-textile applications of dyes, Direct Black-EW, Direct Green, Direct Blue-2B, Direct violet-R, Tartarazine, Amarnath, Direct Brown-MR, Auramine O & G, Methylene Blue, Mercurochrome, Phenolphthalein, Methyl organge, Fast sulphone black, Benzidine yellow, Benzidine orange, Indigo solution blue, Brown-RRD, Alizarin, Benzanthone, Dibenzanthone, Caledon-Z Green. Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-III (Chemistry)
Organic Chemistry
In force from June-2008
Total Marks: 100
Paper-XII
Practicals, Organic Chemistry

Practical based on following topics:
Organic preparations involving two or three steps, (minimum ten) Viva-voce (Questions based on general aspects and fundamentals of organic chemistry) Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-IV (Chemistry)
Organic Chemistry
In force from November-2008
Total Marks: 100
Paper –XIII Natural Product - II
Lectures: 60

Unit –I
Natural pigments:
12
Introduction to natural pigment: pyrrole and polyene pigments, constitution of α, β and γ carotenes and constitution of lycopene, constitution of haemin with synthesis, constitution of chlorophyll.
Unit –II
Steroids:
12
Introduction to steroids and Diel’s hydrocarbon, definition of sterols, steroids, constitution of cholesterol, constitution of ergosterol, chemistry of vitamin D group, introduction and importance of bile pigments and bile acids.
Unit – III
Hormones:
12
Introduction to hormones, chemistry of sex hormones (oestrone, progesterone), chemistry of androgens(androsterone and testosterone), chemistry of adrenaline, thyroxine, chemistry stilboestrol, hexoestrol and ACTH
Unit – IV
Nucleic acids:
12
Detailed study of structure of nucleosides and nucleotides with their synthesis, hydrolysis of nucleic acids under different conditions, structure of DNA and RNA, Biosynthesis of proteins and genetic continuity.
Unit – V
A. Vitamin B group of compounds:
06

Elucidation of the structure and synthesis of vitamins B1, B2,B6, and Biotin.
Biochemical importance of these vitamins
B. Alkaloids
Elucidation of the structure of morphine and cholchicine (analytical evidence only) Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-IV (Chemistry)
Organic Chemistry
In force from November-2008
Total Marks: 100
Paper – XIV Drugs
Lectures: 60

Unit – I
12

A. Introduction to chemotherapy, detailed account of drugs from the view point

Unit –II
12
Analgesics and antipyretics Hypoglycemics Purgatives Antihistamines.
Unit – III
12

Unit – IV
12

Unit – V
12
Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-IV (Chemistry)
Organic Chemistry
In force from November-2008
Total Marks: 100
Paper – XV Selected Topics – II
Lectures: 60

Unit –I
Preparation and isolation of some clinically used drugs
12
Salicylic acid, aspirin, methylsalicylate, d-propoxyphene hydrochloride, acetanilide, 4 – aminophenol, paracetamol, saccharin, caffeine, camphor, insulin, morphine, codeine and cocaine
Unit – II
A) Structure activity relation, an introduction to QSAR. Drug design
Unit –III
Enzymes:
12
Nomenclature, classification of enzymes, chemical nature of co-enzymes-I and II, carboxylase, FAD, ATP, AMP, metallo-enzymes, mechanism of enzyme action, specificity of enzymes.
Unit –IV
A) Introduction to nano-materials and their size. The fundamental science
behind nanotechnology
B) Introduction to disconnections, concept of synthons, synthetic equivalent, functional group inter conversions, concept and design of synthesis, criteria of good disconnection
Unit –V
Fundamentals of Patent:
Definition and concept of patent system, Procedure for patent system, Procedures for patent applications in India, US and Europe, Patentability in India, US and Europe, Infringement and remedies of patent search. Bhavnagar
University
Bhavnagar
SYLLABUS FOR M. Sc.-Semester-IV (Chemistry)
Organic Chemistry
In force from November-2008
Total Marks: 100

Paper-XVI
Practicals, Organic Chemistry


Practical based on following topics:
Separation of three component organic mixtures and identification of the given
components (solid, semisolid and liquid) (minimum 10)

Estimation of mixtures like acid + ketone, acid + ester, and acid + amide 15 marks
Estimation of drugs & Estimation of glucose and sucrose Viva-voce (Questions based on topics of organic chemistry covered in semester I to IV)

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